FBXW5 Antikörper (N-Term)

Produktnummer ABIN5516989

Produktdetails anti-FBXW5 Antikörper

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NDLTISLLHS ADMRPYNWSY TQFSQFNKDD SLLLASGVFL GPHNSSSGEI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXW5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXW5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXW5

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Andere Bezeichnung: FBXW5 (FBXW5 Produkte)

Synonyme: Fbw5 antikoerper, AI159739 antikoerper, F-box and WD repeat domain containing 5 antikoerper, F-box and WD-40 domain protein 5 antikoerper, FBXW5 antikoerper, Fbxw5 antikoerper

Hintergrund: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

Alias Symbols: FBXW5, FBW5, PP3971,

Protein Interaction Partner: KRT40, KRTAP9-4, ADAMTSL4, CUL1, UBC, TRIM27, KRT31, NOTCH2NL, KRTAP10-3, KRTAP10-8, CUL3, SKP1, TNFAIP8L1, TSC2, DLC1, HSP90AA1, NEDD8, MAP3K7, CUL4A, REST, MYB, DDB1, UBE2R2, SASS6, PLK4, CDC20, WDR20, KRTAP4-12, MDFI, TSC1, NLK,

Protein Size: 566

Gen-ID: 54461