FBXW5 Antikörper (N-Term)

Produktnummer ABIN5516989

Der Kaninchen Polyklonal anti-FBXW5 Antikörper wird verwendet zum Nachweis von FBXW5 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für FBXW5 Antikörper (N-Term) (ABIN5516989)

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXW5 Antikörper

Bindungsspezifität: N-Term

Sequenz: NDLTISLLHS ADMRPYNWSY TQFSQFNKDD SLLLASGVFL GPHNSSSGEI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXW5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXW5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXW5

Target: FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))

Andere Bezeichnung: FBXW5

Hintergrund: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

Alias Symbols: FBXW5, FBW5, PP3971,

Protein Interaction Partner: KRT40, KRTAP9-4, ADAMTSL4, CUL1, UBC, TRIM27, KRT31, NOTCH2NL, KRTAP10-3, KRTAP10-8, CUL3, SKP1, TNFAIP8L1, TSC2, DLC1, HSP90AA1, NEDD8, MAP3K7, CUL4A, REST, MYB, DDB1, UBE2R2, SASS6, PLK4, CDC20, WDR20, KRTAP4-12, MDFI, TSC1, NLK,

Protein Size: 566

Gen-ID: 54461