Der Kaninchen Polyklonal Anti-GLDC-Antikörper wurde für WB validiert. Er ist geeignet, GLDC in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN5516905
Kurzübersicht für GLDC Antikörper (C-Term) (ABIN5516905)
GLDC
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
GLDC
(Glycine Dehydrogenase (GLDC))
Andere Bezeichnung
GCSP
Hintergrund
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Alias Symbols: GLDC, GCSP,
Protein Interaction Partner: SUZ12, UBC, CUL2, TNFAIP3, TLR10, GLDC,