ITGB3BP Antikörper (N-Term)

Produktnummer ABIN5516800

Der Kaninchen Polyklonal anti-ITGB3BP Antikörper wird verwendet zum Nachweis von ITGB3BP in Proben von Human und Hund. Er wurde validiert für WB.

Kurzübersicht für ITGB3BP Antikörper (N-Term) (ABIN5516800)

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ITGB3BP Antikörper

Bindungsspezifität: N-Term

Sequenz: QMSLFASPTS SEEQKHRNGL SNEKRKKLNH PSLTESKEST TKDNDEFMML

Homologie: Dog: 91%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ITGB3BP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ITGB3BP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ITGB3BP

Target: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Andere Bezeichnung: ITGB3BP

Hintergrund: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Alias Symbols: ITGB3BP, CENPR, NRIF3,

Protein Interaction Partner: PIH1D2, UBR7, ARFIP2, COL4A3BP, KIFC3, KDM1A, UBC, APP, CENPP, CENPO, SVIL, MAPK6, ACTN2, MTA1, ITGB3BP, DDX24, RECQL5, RXRA, ITGB3, NFKB1, ITGB5, ESR1, CCNA2, THRA, RELA, RXRG,

Protein Size: 216

Gen-ID: 23421

NCBI Accession: NP_055103

Pathways: Neurotrophin Signalübertragung