SLC16A2/MCT8 Antikörper (N-Term)

Produktnummer ABIN5516550

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC16A2/MCT8 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SLC16A2/MCT8 Antikörper (N-Term) (ABIN5516550)

Target: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC16A2/MCT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SLC16A2/MCT8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SLC16A2 Antibody - N-terminal region

Sequenz: EPEPVPVPPP EPQPEPQPLP DPAPLPELEF ESERVHEPEP TPTVETRGTA

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC16A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80952-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SLC16A2/MCT8

Target: SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))

Andere Bezeichnung: SLC16A2

Hintergrund:

Background Information: This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.

Gene Name: solute carrier family 16, member 2 (thyroid hormone transporter)

Alternative Symbols: AHDS, MCT7, MCT8, XPCT, MCT 7, MCT 8, MRX22, DXS128, DXS128E

Protein Name: monocarboxylate transporter 8

Molekulargewicht: 59 kDa

Gen-ID: 6567

NCBI Accession: NP_006508

UniProt: P36021

Pathways: Hormone Transport