CD1c Antikörper (C-Term)

Produktnummer ABIN5516504

Dieses Anti-CD1c-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD1c in WB. Geeignet für Human und Ratte.

Kurzübersicht für CD1c Antikörper (C-Term) (ABIN5516504)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1c Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD1c Antikörper

Bindungsspezifität: C-Term

Sequenz: ASGFYPKPVW VTWMRNEQEQ LGTKHGDILP NADGTWYLQV ILEVASEEPA

Homologie: Human: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CD1C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Andere Bezeichnung: CD1C

Hintergrund: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Alias Symbols: BDCA1, CD1, CD1A, R7

Protein Size: 333

Gen-ID: 911

NCBI Accession: NM_001765, NP_001756

UniProt: P29017