ARVCF Antikörper (C-Term)

Produktnummer ABIN5516447

Der Kaninchen Polyklonal anti-ARVCF Antikörper (ABIN5516447) detektiert spezifisch ARVCF in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ARVCF Antikörper (C-Term) (ABIN5516447)

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARVCF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARVCF Antikörper

Bindungsspezifität: C-Term

Sequenz: GPDGYSTVDR RERRPRGASS AGEASEKEPL KLDPSRKAPP PGPSRPAVRL

Produktmerkmale: This is a rabbit polyclonal antibody against ARVCF. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARVCF

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARVCF

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Andere Bezeichnung: ARVCF

Hintergrund: Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.

Alias Symbols: Name=ARVCF,

Protein Interaction Partner: ERBB2IP, UBC, LNX1, TJP1, CDH1, CDH2, CDH15,

Protein Size: 962

Gen-ID: 421

NCBI Accession: NP_001661

UniProt: O00192