HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) Antikörper

Produktnummer ABIN5516370

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HERV-FRD Provirus Ancestral Env Polyprotein in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) Antikörper (ABIN5516370)

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: ERVFRD-1 Antibody - C-terminal region

Sequenz: PLVSLLLLLL FGPCLLNLIT QFVSSRLQAI KLQTNLSAGR HPRNIQESPF

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ERVFRD-1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERVFRD-1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56009-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Andere Bezeichnung: ERVFRD-1

Hintergrund:

Background Information: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Gene Name: endogenous retrovirus group FRD, member 1

Alternative Symbols: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD

Protein Name: HERV-FRD_6p24.1 provirus ancestral Env polyprotein

Molekulargewicht: 59kDa

Gen-ID: 405754

NCBI Accession: NP_997465

UniProt: P60508