HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) Antikörper
Kurzübersicht für HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) Antikörper (ABIN5516370)
Target
Alle HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- PLVSLLLLLL FGPCLLNLIT QFVSSRLQAI KLQTNLSAGR HPRNIQESPF
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ERVFRD-1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERVFRD-1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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Andere Bezeichnung
- ERVFRD-1
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Hintergrund
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Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Alias Symbols: ERVFRD-1, ERVFRDE1, UNQ6191/PRO20218,
Protein Interaction Partner: APP,
Protein Size: 538 -
Gen-ID
- 405754
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NCBI Accession
- NP_997465
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UniProt
- P60508
Target
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