DPM2 Antikörper (Middle Region)

Produktnummer ABIN5516306

Der Kaninchen Polyklonal anti-DPM2 Antikörper (ABIN5516306) detektiert spezifisch DPM2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DPM2 Antikörper (Middle Region) (ABIN5516306)

Target: DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DPM2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DPM2

Target: DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

Andere Bezeichnung: DPM2

Hintergrund: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.

Alias Symbols: CDG1U

Protein Size: 84

Gen-ID: 8818

NCBI Accession: NM_003863, NP_003854

UniProt: O94777

Pathways: Inositol Metabolic Process