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DPM2 Antikörper (Middle Region)

Dieses Anti-DPM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DPM2 in WB. Geeignet für Human.
Produktnummer ABIN5516306

Kurzübersicht für DPM2 Antikörper (Middle Region) (ABIN5516306)

Target

Alle DPM2 Antikörper anzeigen
DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

Reaktivität

  • 1
  • 1
Human

Wirt

  • 2
Kaninchen

Klonalität

  • 2
Polyklonal

Konjugat

  • 2
Dieser DPM2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB)
  • Bindungsspezifität

    Middle Region

    Sequenz

    DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ

    Aufreinigung

    Affinity purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human DPM2
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))

    Andere Bezeichnung

    DPM2

    Hintergrund

    Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.

    Alias Symbols: CDG1U

    Protein Size: 84

    Gen-ID

    8818

    NCBI Accession

    NM_003863, NP_003854

    UniProt

    O94777

    Pathways

    Inositol Metabolic Process
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