CKMT1B Antikörper (N-Term)

Produktnummer ABIN5516114

Produktdetails anti-CKMT1B Antikörper

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVGMVAGDEE TYEVFADLFD PVIQERHNGY DPRTMKHTTD LDASKIRSGY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CKMT1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CKMT1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CKMT1B

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Andere Bezeichnung: CKMT1B (CKMT1B Produkte)

Synonyme: CKMT antikoerper, CKMT1 antikoerper, UMTCK antikoerper, ckmt antikoerper, ckmt1 antikoerper, umtck antikoerper, CKMT1A antikoerper, creatine kinase, mitochondrial 1B antikoerper, creatine kinase, mitochondrial 1B S homeolog antikoerper, creatine kinase, mitochondrial 1B L homeolog antikoerper, CKMT1B antikoerper, ckmt1b.S antikoerper, ckmt1b.L antikoerper, ckmt1b antikoerper

Hintergrund: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Protein Interaction Partner: UBC, ASB9, BMI1, HECW2, IQCB1, gag-pol, IGBP1, CUL3, CALM1, HDAC5,

Protein Size: 417

Gen-ID: 1159

NCBI Accession: XP_005254554

UniProt: P12532