PAK6 Antikörper (C-Term)

Produktnummer ABIN5516055

Produktdetails anti-PAK6 Antikörper

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Ziege, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRDFLERMLV RDPQERATAQ ELLDHPFLLQ TGLPECLVPL IQLYRKQTST

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PAK6. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAK6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6 (PAK6 Produkte)

Synonyme: PAK5 antikoerper, 4732456M09 antikoerper, pak6 antikoerper, si:ch211-158b22.3 antikoerper, p21 (RAC1) activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6b antikoerper, PAK6 antikoerper, Pak6 antikoerper, pak6b antikoerper

Hintergrund: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Alias Symbols: PAK6, PAK5,

Protein Interaction Partner: RHOJ, RAC1, NEK6, SEMA3B, TPD52L1, SNX2, HSP90AA1, CDK1, MDM2, AR, APP, LNX1, MYC, MAPK14, CDC42, ESR1, AKT1, YWHAQ,

Protein Size: 681

Gen-ID: 56924

NCBI Accession: NP_064553

UniProt: Q9NQU5