IKAP/p150 Antikörper (C-Term)
Kurzübersicht für IKAP/p150 Antikörper (C-Term) (ABIN5516011)
Target
Alle IKAP/p150 (ELP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- SRISARSSKN RRKAERKKHS LKEGSPLEDL ALLEALSEVV QNTENLKDEV
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Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against IKBKAP. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of human IKBKAP
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))
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Andere Bezeichnung
- IKBKAP
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Hintergrund
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The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: FD, DYS, ELP1, IKAP, IKI3, TOT1
Protein Size: 346 -
Gen-ID
- 8518
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NCBI Accession
- NM_003640, NP_003631
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UniProt
- O95163
Target
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