IKAP/p150 Antikörper (C-Term)

Produktnummer ABIN5516011

Produktdetails anti-IKAP/p150 Antikörper

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKAP/p150 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SRISARSSKN RRKAERKKHS LKEGSPLEDL ALLEALSEVV QNTENLKDEV

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IKBKAP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human IKBKAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IKAP/p150

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Andere Bezeichnung: IKBKAP (ELP1 Produkte)

Synonyme: DYS antikoerper, ELP1 antikoerper, FD antikoerper, IKAP antikoerper, IKI3 antikoerper, TOT1 antikoerper, IKBKAP antikoerper, DKFZp469N1415 antikoerper, 3110040G09Rik antikoerper, 6030413P05 antikoerper, C78473 antikoerper, Elp1 antikoerper, Ikbkap antikoerper, elongator complex protein 1 antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein antikoerper, ielongator complex protein 1 S homeolog antikoerper, inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein antikoerper, ELP1 antikoerper, Elp1 antikoerper, IKBKAP antikoerper, elp1.S antikoerper, elp1 antikoerper, Ikbkap antikoerper

Hintergrund: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: FD, DYS, ELP1, IKAP, IKI3, TOT1

Protein Size: 346

Gen-ID: 8518

NCBI Accession: NM_003640, NP_003631

UniProt: O95163