DDX11 Antikörper (N-Term)

Produktnummer ABIN5515964

Der Kaninchen Polyklonal anti-DDX11 Antikörper (ABIN5515964) detektiert spezifisch DDX11 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DDX11 Antikörper (N-Term) (ABIN5515964)

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DDX11 Antikörper

Bindungsspezifität: N-Term

Sequenz: TQKVGAIHFP FPFTPYSIQE DFMAELYRVL EAGKIGIFES PTGTGKSLSL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DDX11

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Andere Bezeichnung: DDX11

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: CHL1, KRG2, WABS, CHLR1

Protein Size: 856

Gen-ID: 1663

NCBI Accession: NM_001257144, NP_001244073

Pathways: ER-Nucleus Signaling