CDC14B Antikörper (N-Term)

Produktnummer ABIN5515888

Der Kaninchen Polyklonal anti-CDC14B Antikörper wird verwendet zum Nachweis von CDC14B in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CDC14B Antikörper (N-Term) (ABIN5515888)

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC14B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDC14B Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CDC14B Antibody - N-terminal region

Sequenz: RCSSTSPGVK KIRSSTQQDP RRRDPQDDVY LDITDRLCFA ILYSRPKSAS

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC14B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80337-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC14B

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Andere Bezeichnung: CDC14B

Hintergrund:

Background Information: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Gene Name: cell division cycle 14B

Alternative Symbols: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B

Protein Name: dual specificity protein phosphatase CDC14B

Molekulargewicht: 53 kDa

Gen-ID: 8555

NCBI Accession: NP_001070649

UniProt: O60729