AIPL1 Antikörper (C-Term)

Produktnummer ABIN5515809

Produktdetails anti-AIPL1 Antikörper

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIPL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DLDELQKEPQ PLVFVIELLQ VDAPSDYQRE TWNLSNHEKM KAVPVLHGEG

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Mouse: 77%, Pig: 86%, Rabbit: 79%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against AIPL1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human AIPL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AIPL1

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Andere Bezeichnung: AIPL1 (AIPL1 Produkte)

Synonyme: AIPL1 antikoerper, lca4 antikoerper, aipl2 antikoerper, AIPL2 antikoerper, LCA4 antikoerper, A930007I01Rik antikoerper, aryl hydrocarbon receptor interacting protein like 1 antikoerper, aryl hydrocarbon receptor-interacting protein-like 1 antikoerper, AIPL1 antikoerper, aipl1 antikoerper, Aipl1 antikoerper

Hintergrund: Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5 % of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20 % of recessive LCA. Alternative splicing results in multiple transcript variants.

Alias Symbols: LCA4, AIPL2

Protein Size: 270

Gen-ID: 23746

NCBI Accession: NM_001285403, NP_001272332

UniProt: F1T0C4