RTEL1 Antikörper (C-Term)

Produktnummer ABIN5515690

Der Kaninchen Polyklonal anti-RTEL1 Antikörper wird verwendet zum Nachweis von RTEL1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für RTEL1 Antikörper (C-Term) (ABIN5515690)

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTEL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RTEL1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RTEL1 Antibody - C-terminal region

Sequenz: QGRPHLSPRP PPTGDPGSQP QWGSGVPRAG KQGQHAVSAY LADARRALGS

Produktmerkmale: This is a rabbit polyclonal antibody against RTEL1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RTEL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74195-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Andere Bezeichnung: RTEL1

Hintergrund:

Background Information: This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative Symbols: NHL, RTEL, DKCA4, DKCB5, PFBMFT3, C20orf41

Molekulargewicht: 109kDa

Gen-ID: 51750

UniProt: Q9NZ71