SSTR5 Antikörper (Middle Region)
Kurzübersicht für SSTR5 Antikörper (Middle Region) (ABIN5515665)
Target
Alle SSTR5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- FAPLLVICLC YLLIVVKVRA AGVRVGCVRR RSERKVTRMV LVVVLVFAGC
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 77%, Rat: 100%, Sheep: 100%, Zebrafish: 92%
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SSR5
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SSTR5 (Somatostatin Receptor 5 (SSTR5))
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Andere Bezeichnung
- SSTR5
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Hintergrund
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Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
Alias Symbols: SS-5-R
Protein Interaction Partner: UBC, SST, GOPC, ADCY10, PDZK1, CORT, PEX5, SSTR5, SSTR1, DRD2,
Protein Size: 364 -
Gen-ID
- 6755
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NCBI Accession
- NM_001053, NP_001044
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UniProt
- P35346
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Pathways
- Carbohydrate Homeostasis
Target
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