SPG7 Antikörper (N-Term)

Produktnummer ABIN5515659

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPG7 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SPG7 Antikörper (N-Term) (ABIN5515659)

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPG7 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SPG7 Antibody - N-terminal region

Sequenz: LWQLLGGTFY FNTSRLKQKN KEKDKSKGKA PEEDEEERRR RERDDQMYRE

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPG7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81354-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Andere Bezeichnung: SPG7

Hintergrund:

Background Information: This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

Gene Name: spastic paraplegia 7 (pure and complicated autosomal recessive)

Alternative Symbols: CAR, PGN, CMAR, SPG5C

Protein Name: paraplegin

Molekulargewicht: 53 kDa

Gen-ID: 6687

NCBI Accession: NP_003110

UniProt: Q9UQ90