ANO1 Antikörper (C-Term)

Produktnummer ABIN5515653

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ANO1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ANO1 Antikörper (C-Term) (ABIN5515653)

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ANO1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ANO1 Antibody - C-terminal region

Sequenz: LMVELFMREE QDKQQLLETW MEKERQKDEP PCNHHNTKAC PDSLGSPAPS

Produktmerkmale: This is a rabbit polyclonal antibody against ANO1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ANO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72448-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ANO1

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Andere Bezeichnung: ANO1

Hintergrund:

Background Information: ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. It acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.

Alternative Symbols: DOG1, TAOS2, ORAOV2, TMEM16A

Molekulargewicht: 108kDa

Gen-ID: 55107

NCBI Accession: NP_060513

UniProt: Q5XXA6