PCDHb5 Antikörper (N-Term)

Produktnummer ABIN5515617

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PCDHb5 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen und Kaninchen.

Kurzübersicht für PCDHb5 Antikörper (N-Term) (ABIN5515617)

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHb5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHb5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PCDHB5 Antibody - N-terminal region

Sequenz: QFFQTDLQLT DINDHAPEFP EKEMLLKIPE STQPGTVFPL KIAQDFDIGS

Homologie: Cow: 77%, Guinea Pig: 85%, Human: 100%, Mouse: 92%, Rabbit: 75%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDHB5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PCDHB5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47179-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PCDHb5

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Andere Bezeichnung: PCDHB5

Hintergrund:

Background Information: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Gene Name: protocadherin beta 5

Alternative Symbols: PCDH-BETA5

Protein Name: Protocadherin beta-5

Molekulargewicht: 87kDa

Gen-ID: 26167

NCBI Accession: NP_056484

UniProt: Q9Y5E4