CCAR1 Antikörper (C-Term)

Produktnummer ABIN5515401

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCAR1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Schwein und Meerschweinchen.

Kurzübersicht für CCAR1 Antikörper (C-Term) (ABIN5515401)

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCAR1 Antikörper

Bindungsspezifität: C-Term

Sequenz: YDPMEAEEAE DEEDDRDEEE MTKRDDKRDI NRYCKERPSK DKEKEKTQMI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CCAR1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Andere Bezeichnung: CCAR1

Hintergrund: CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity). It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation.

Alias Symbols: CARP1, DIS

Protein Interaction Partner: PIH1D3, GOLGA2, SUMO2, SUMO3, UBC, TP53, MDM2, U2AF2, CHERP, UBL4A, RBM10, RNF113A, HNRNPK, SMURF1, BARD1, SIRT7, SF3A2, Kif23, FYCO1, CASP10, SFN, YWHAQ,

Protein Size: 1150

Gen-ID: 55749

NCBI Accession: NP_060707

UniProt: Q8IX12