Azurocidin Antikörper (Middle Region)
Kurzübersicht für Azurocidin Antikörper (Middle Region) (ABIN5515391)
Target
Alle Azurocidin (AZU1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- AZU1 Antibody - middle region
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Sequenz
- QSQNPGVSTV VLGAYDLRRR ERQSRQTFSI SSMSENGYDP QQNLNDLMLL
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Homologie
- Cow: 100%, Horse: 75%, Human: 100%, Pig: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AZU1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AZU1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73078-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
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Andere Bezeichnung
- AZU1
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Hintergrund
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Background Information: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Gene Name: azurocidin 1
Alternative Symbols: AZU, HBP, NAZC, hHBP, AZAMP, CAP37, HUMAZUR
Protein Name: azurocidin
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Molekulargewicht
- 24kDa
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Gen-ID
- 566
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NCBI Accession
- NP_001691
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UniProt
- P20160
Target
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