Azurocidin Antikörper (Middle Region)

Produktnummer ABIN5515391

Der Kaninchen Polyklonal anti-Azurocidin Antikörper (ABIN5515391) detektiert spezifisch Azurocidin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Pferd und Schwein.

Kurzübersicht für Azurocidin Antikörper (Middle Region) (ABIN5515391)

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Reaktivität: Human, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Azurocidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Azurocidin Antikörper

Bindungsspezifität: Middle Region

Sequenz: QSQNPGVSTV VLGAYDLRRR ERQSRQTFSI SSMSENGYDP QQNLNDLMLL

Homologie: Cow: 100%, Horse: 75%, Human: 100%, Pig: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against AZU1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AZU1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Andere Bezeichnung: AZU1

Hintergrund: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Alias Symbols: AZU, HBP, NAZC, hHBP, AZAMP, CAP37, HUMAZUR

Protein Size: 226

Gen-ID: 566

NCBI Accession: NM_001700, NP_001691

UniProt: P20160