AXIN2 Antikörper (C-Term)
Kurzübersicht für AXIN2 Antikörper (C-Term) (ABIN5515389)
Target
Alle AXIN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- QWMLESERQS KPKPHSAQST KKAYPLESAR SSPGERASRH HLWGGNSGHP
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AXIN2. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human AXIN2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AXIN2 (Axin 2 (AXIN2))
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Andere Bezeichnung
- AXIN2
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Hintergrund
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AXIN2 is a inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. It probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).
Alias Symbols: AXIN2,
Protein Interaction Partner: FBXW11, GSK3B, GSK3A, UBC, CDC20, AXIN1, KDM5B, ANKRD6, SMAD3, CSNK1E, APC, CTNNB1, APC2, ESR1,
Protein Size: 843 -
Gen-ID
- 8313
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NCBI Accession
- NP_004646
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UniProt
- Q9Y2T1
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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