ST5 Antikörper (N-Term)

Produktnummer ABIN5515162

Der Kaninchen Polyklonal Anti-ST5-Antikörper wurde für WB validiert. Er ist geeignet, ST5 in Proben von Human zu detektieren.

Kurzübersicht für ST5 Antikörper (N-Term) (ABIN5515162)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ST5 Antikörper

Bindungsspezifität: N-Term

Sequenz: TSACRYPSHS SSRVLLKDRH PPAPSPQNPQ DPSPDTSPPT CPFKTASFGY

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ST5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Andere Bezeichnung: ST5

Hintergrund: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Alias Symbols: HTS1, p126, DENND2B

Protein Size: 1137

Gen-ID: 6764

NCBI Accession: NM_005418, NP_005409

UniProt: P78524