RASA3 Antikörper (N-Term)

Produktnummer ABIN5515101

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RASA3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RASA3 Antikörper (N-Term) (ABIN5515101)

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASA3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RASA3 Antibody - N-terminal region

Sequenz: YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL

Produktmerkmale: This is a rabbit polyclonal antibody against RASA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74174-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RASA3

Target: RASA3 (RAS P21 Protein Activator 3 (RASA3))

Andere Bezeichnung: RASA3

Hintergrund:

Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Alternative Symbols: GAPIII, GAP1IP4BP

Molekulargewicht: 91kDa

Gen-ID: 22821

NCBI Accession: NP_031394

UniProt: Q14644