RAB6A Antikörper (C-Term)

Produktnummer ABIN5515093

Der Kaninchen Polyklonal anti-RAB6A Antikörper wird verwendet zum Nachweis von RAB6A in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für RAB6A Antikörper (C-Term) (ABIN5515093)

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAB6A Antikörper

Bindungsspezifität: C-Term

Sequenz: ERKAKELNVM FIETSAKAGY NVKQLFRRVA AALPGMESTQ DRSREDMIDI

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RAB6A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAB6A

Target: RAB6A (RAB6A, Member RAS Oncogene Family (RAB6A))

Andere Bezeichnung: RAB6A

Hintergrund: This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alias Symbols: RAB6

Protein Size: 167

Gen-ID: 5870

NCBI Accession: NM_001243718, NP_001230647

UniProt: P20340