PTPMT1 Antikörper (N-Term)

Produktnummer ABIN5515057

Der Kaninchen Polyklonal anti-PTPMT1 Antikörper wird verwendet zum Nachweis von PTPMT1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PTPMT1 Antikörper (N-Term) (ABIN5515057)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PTPMT1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PTPMT1 Antibody - N-terminal region

Sequenz: LFYPTLLYTL FRGKVPGRAH RDWYHRIDPT VLLGALPLRS LTRQLVQDEN

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTPMT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79956-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Andere Bezeichnung: PTPMT1

Hintergrund:

Background Information: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).

Gene Name: protein tyrosine phosphatase, mitochondrial 1

Alternative Symbols: MOSP, PLIP, DUSP23, PNAS-129

Protein Name: phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Molekulargewicht: 23 kDa

Gen-ID: 114971

NCBI Accession: NP_001137456

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process