Der Kaninchen Polyklonal Anti-PDZRN3-Antikörper wurde für WB validiert. Er ist geeignet, PDZRN3 in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen und Pferd zu detektieren.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PDZRN3
(PDZ Domain Containing Ring Finger 3 (PDZRN3))
Andere Bezeichnung
PDZRN3
Hintergrund
PDZRN3 is an E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.