UBTF Antikörper (C-Term)

Produktnummer ABIN5515000

Der Kaninchen Polyklonal anti-UBTF Antikörper wird verwendet zum Nachweis von UBTF in Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schwein, Saccharomyces cerevisiae und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für UBTF Antikörper (C-Term) (ABIN5515000)

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schwein, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UBTF Antikörper

Bindungsspezifität: C-Term

Sequenz: SEDGGDSSES SSEDESEDGD ENEEDDEDED DDEDDDEDED NESEGSSSSS

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against UBF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Andere Bezeichnung: UBF1

Hintergrund: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Alias Symbols: UBTF, UBF, UBF1,

Protein Interaction Partner: UBC, MDM2, RNF2, Dlg4, ESR1, CDK4, CDK2, CCNE1, CCND1, WDR70, YEATS4, RB1, GRK5, KAT5, SIRT7, POLR1A, MYBBP1A, HDAC1, RUNX2, SUMO2, SMARCA5, MAPK3, MAPK1, SUMO1, PIK3CA, IRS1, TAF1D, tat, MCRS1, TLE1, ACTN4, POLR1E, CHGB, SMURF1, TCOF1, MAD1L1, ZMYM2, SER

Protein Size: 764

Gen-ID: 7343

NCBI Accession: XP_006722124

UniProt: P17480