MDFI Antikörper (Middle Region)

Produktnummer ABIN5514974

Der Kaninchen Polyklonal anti-MDFI Antikörper (ABIN5514974) detektiert spezifisch MDFI in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Hund, Schwein, Kaninchen und Schaf.

Kurzübersicht für MDFI Antikörper (Middle Region) (ABIN5514974)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MDFI Antikörper

Bindungsspezifität: Middle Region

Sequenz: AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH

Homologie: Cow: 79%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MDFI. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MDFI

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Andere Bezeichnung: MDFI

Hintergrund: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Alias Symbols: MDFI,

Protein Interaction Partner: PDIA5, USP20, ARID5A, ZNF266, KAT5, SPRY2, SPRY1, NR1H3, ZBTB24, ARHGAP32, KIAA0040, CREB5, MAGED1, ZNF264, GTF3C5, APLN, AKAP17A, ZNF230, ZNF223, ZNF155, ZNF138, ZNF136, ZNF124, ZNF79, WNT11, VHL, NR1H2, TYRO3, TNP2, TNNI1, TGIF1, GNAI2, GATA2, EIF4A2, D

Protein Size: 246

Gen-ID: 4188

NCBI Accession: NP_005577

UniProt: Q99750

Pathways: Maintenance of Protein Location