Muscarinic Acetylcholine Receptor M2 Antikörper (N-Term)

Produktnummer ABIN5514972

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Muscarinic Acetylcholine Receptor M2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Muscarinic Acetylcholine Receptor M2 Antikörper (N-Term) (ABIN5514972)

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Muscarinic Acetylcholine Receptor M2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Muscarinic Acetylcholine Receptor M2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CHRM2 Antibody - N-terminal region

Sequenz: MNNSTNSSNN SLALTSPYKT FEVVFIVLVA GSLSLVTIIG NILVMVSIKV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81294-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Andere Bezeichnung: CHRM2

Hintergrund:

Background Information: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

Gene Name: cholinergic receptor, muscarinic 2

Alternative Symbols: HM2

Protein Name: muscarinic acetylcholine receptor M2

Molekulargewicht: 51 kDa

Gen-ID: 1129

NCBI Accession: NP_000730

UniProt: P08172