MYRIP Antikörper (Middle Region)
Kurzübersicht für MYRIP Antikörper (Middle Region) (ABIN5514958)
Target
Alle MYRIP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- MYRIP Antibody - middle region
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Sequenz
- RRARLGSEEP SKEPSSPSAQ LRDLDTHQVS DDLSETDISN EARDPQTLTD
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Homologie
- Dog: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MYRIP. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human MYRIP
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59446-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MYRIP (Myosin VIIA and Rab Interacting Protein (MYRIP))
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Andere Bezeichnung
- MYRIP
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Hintergrund
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Background Information: MYRIP is a rab effector protein involved in melanosome transport. It Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. It functions as a protein kinase A-anchoring protein (AKAP). It may act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity).
Gene Name: myosin VIIA and Rab interacting protein
Alternative Symbols: SLAC2C, SLAC2-C
Protein Name: Rab effector MyRIP
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Molekulargewicht
- 73kDa
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Gen-ID
- 25924
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UniProt
- Q8NFW9
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
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