LIM Domain Binding 1 Protein Antikörper (C-Term)

Produktnummer ABIN5514920

Dieses Anti-LIM Domain Binding 1 Protein-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LIM Domain Binding 1 Protein in WB. Geeignet für Human.

Kurzübersicht für LIM Domain Binding 1 Protein Antikörper (C-Term) (ABIN5514920)

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIM Domain Binding 1 Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LIM Domain Binding 1 Protein Antikörper

Bindungsspezifität: C-Term

Sequenz: VAPPAEPTRQ QPSKRRKRKM SGGSTMSSGG GNTNNSNSKK KSPASTFALS

Produktmerkmale: This is a rabbit polyclonal antibody against LDB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LIM Domain Binding 1 Protein

Target: LIM Domain Binding 1 Protein (LDB1) (LIM Domain Binding 1 (LDB1))

Andere Bezeichnung: LDB1

Hintergrund: LDB1 binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. It may regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. It plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. It acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. It acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.

Alias Symbols: LDB1, CLIM2,

Protein Interaction Partner: LHX8, LHX6, SSBP3, LMO4, LMX1B, LMO2, LMO1, POLR1B, LSM7, IRAK3, UBC, PSMD10, PSMA1, TRIM33, ATXN1, RNF38, RNF6, rlim-a, RLIM, RB1, TAL1, LHX2, LMO3, SSBP4, SSBP2, TOLLIP, CTDSP1, LHX3, SSBP1, ISL1, LMX1A, ESR1, TCF3, SP1, CBFA2T3,

Protein Size: 411

Gen-ID: 8861

UniProt: Q86U70

Pathways: Stem Cell Maintenance, Chromatin Binding