KLC1 Antikörper (C-Term)

Produktnummer ABIN5514913

Der Kaninchen Polyklonal anti-KLC1 Antikörper wird verwendet zum Nachweis von KLC1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für KLC1 Antikörper (C-Term) (ABIN5514913)

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLC1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: KLC1 Antibody - C-terminal region

Sequenz: ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KLC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61154-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KLC1

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Andere Bezeichnung: KLC1

Hintergrund:

Background Information: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

Gene Name: kinesin light chain 1

Alternative Symbols: KLC, KNS2, KNS2A

Protein Name: kinesin light chain 1

Molekulargewicht: 60 kDa

Gen-ID: 3831

NCBI Accession: NP_005543

UniProt: Q07866

Pathways: Ribonucleoprotein Complex Subunit Organization