KLC1 Antikörper (C-Term)

Produktnummer ABIN5514913

Der Kaninchen Polyklonal Anti-KLC1-Antikörper wurde für WB validiert. Er ist geeignet, KLC1 in Proben von Human zu detektieren.

Kurzübersicht für KLC1 Antikörper (C-Term) (ABIN5514913)

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLC1 Antikörper

Bindungsspezifität: C-Term

Sequenz: ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KLC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KLC1

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Andere Bezeichnung: KLC1

Hintergrund: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

Alias Symbols: KLC, KNS2, KNS2A,

Protein Interaction Partner: CCDC114, KRT31, BNIP2, UBC, EZH2, TLE3, KIF5B, DIAPH1, COPB1, ARCN1, KLC4, KLC2, SMEK2, PTPN23, COPZ1, APP, RIC3, BSDC1, FAM63B, PRKAG3, LDLRAP1, RASSF8, YWHAE, SKP1, SNCA, KIF5A, MAPK6, YWHAB, LRSAM1, MAPK8IP3, PLEKHM2, CLSTN1, SPAG9, MAPK8IP2, MAPK8IP1,

Protein Size: 551

Gen-ID: 3831

NCBI Accession: NM_001130107, NP_005543

Pathways: Ribonucleoprotein Complex Subunit Organization