HRH1 Antikörper (C-Term)

Produktnummer ABIN5514867

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HRH1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HRH1 Antikörper (C-Term) (ABIN5514867)

Target: HRH1 (Histamine Receptor H1 (HRH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HRH1 Antikörper

Bindungsspezifität: C-Term

Sequenz: SSWPSPTEPS SKSGNLRHLH ILIGTSVVKI PFTILLFFLL HRWCSNKKKC

Homologie: Human: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HRH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HRH1

Target: HRH1 (Histamine Receptor H1 (HRH1))

Andere Bezeichnung: HRH1

Hintergrund: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alias Symbols: H1R, H1-R, HH1R, hisH1

Protein Interaction Partner: UBC,

Protein Size: 487

Gen-ID: 3269

NCBI Accession: NM_000861, NP_000852

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process