Histone H3.3 Antikörper (N-Term)

Produktnummer ABIN5514837

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Histone H3.3 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Histone H3.3 Antikörper (N-Term) (ABIN5514837)

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H3.3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Histone H3.3 Antikörper

Bindungsspezifität: N-Term

Sequenz: RTKQTARKST GGKAPRKQLA TKAARKSAPS TGGVKKPHRY RPGTVALREI

Produktmerkmale: This is a rabbit polyclonal antibody against H3F3A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human H3F3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Histone H3.3

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Andere Bezeichnung: H3F3A

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.

Alias Symbols: H3F3A, H3.3B,

Protein Interaction Partner: FUS, DAXX, CENPA, ATRX, ZMYND11, HIST1H4A, UBC, PML, H2AFY, UHRF1, ASB9, ASB16, ASB2, RNF2, CORO1C, PUF60, NUDC, VPS26A, SNX2, PAWR, VPS35, VPS29, FAM129B, SNX6, ASF1B, ASF1A, HIRA, CHAF1A, ITGA4, HIST4H4, NOS3, LRRK2, HIST1H4F, KDM4A, SSRP1, BRD1, EFS, S

Protein Size: 136

Gen-ID: 3020

NCBI Accession: NP_005315

UniProt: P84243