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GAD65 Antikörper (N-Term)
GAD2
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5514805
Produktdetails anti-GAD65 Antikörper
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Target
Alle GAD65 (GAD2) Antikörper anzeigen
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Bindungsspezifität
Alle Epitope für GAD65 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für GAD65 Antikörper
Human
Wirt
Alle Wirte für GAD65 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GAD65 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GAD65 Antikörper
Dieser GAD65 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GAD65 Antikörper
Western Blotting (WB)
Sequenz
FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
Produktmerkmale
This is a rabbit polyclonal antibody against DCE2. It was validated on Western Blot.
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human DCE2
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Discover our top product GAD2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu GAD65
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Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Andere Bezeichnung
DCE2 (GAD2 Produkte )
Synonyme
GAD65 antikoerper, gad65 antikoerper, F12P19.12 antikoerper, F12P19_12 antikoerper, GLUTAMATE DECARBOXYLASE 2 antikoerper, glutamate decarboxylase 2 antikoerper, zgc:112198 antikoerper, 6330404F12Rik antikoerper, GAD(65) antikoerper, Gad-2 antikoerper, glutamate decarboxylase 2 antikoerper, glutamate decarboxylase 1 antikoerper, glutamic acid decarboxylase 2 antikoerper, GAD2 antikoerper, PTRG_06148 antikoerper, LOC9324534 antikoerper, Gad2 antikoerper, GAD1 antikoerper, gad2 antikoerper
Hintergrund
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. Alias Symbols: GAD2, GAD65, Protein Interaction Partner: CMTM5, MAL2, TMEM159, AGTRAP, ARL6IP1, GAD1, F10, PRKCE, PRKACA, ZDHHC17, Protein Size: 585
Gen-ID
2572
NCBI Accession
NP_001127838
UniProt
Q05329
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