ALPL Antikörper (N-Term)

Produktnummer ABIN5514802

Der Kaninchen Polyklonal anti-ALPL Antikörper wird verwendet zum Nachweis von ALPL in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für ALPL Antikörper (N-Term) (ABIN5514802)

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALPL Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ALPL Antibody - N-terminal region

Sequenz: FLVLAIGTCL TNSLVPEKEK DPKYWRDQAQ ETLKYALELQ KLNTNVAKNV

Produktmerkmale: This is a rabbit polyclonal antibody against PPBT. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PPBT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75902-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: ALPL

Hintergrund:

Background Information: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Gene Name: alkaline phosphatase, biomineralization associated

Alternative Symbols: HOPS, TNAP, TNALP, APTNAP, TNSALP, AP-TNAP

Protein Name: alkaline phosphatase, tissue-nonspecific isozyme

Molekulargewicht: 57kDa

Gen-ID: 249

NCBI Accession: XP_006710609

UniProt: P05186