TDO2 Antikörper (C-Term)

Produktnummer ABIN5514793

Der Kaninchen Polyklonal anti-TDO2 Antikörper wird verwendet zum Nachweis von TDO2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd. Er wurde validiert für WB.

Kurzübersicht für TDO2 Antikörper (C-Term) (ABIN5514793)

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TDO2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TDO2 Antibody - C-terminal region

Sequenz: MDIDSLMTKW RYNHVCMVHR MLGSKAGTGG SSGYHYLRST VSDRYKVFVD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against T23O. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human T23O

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45718-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TDO2

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Andere Bezeichnung: TDO2

Hintergrund:

Background Information: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Gene Name: tryptophan 2,3-dioxygenase

Alternative Symbols: TO, TDO, TPH2, TRPO, HYPTRP

Protein Name: tryptophan 2,3-dioxygenase

Molekulargewicht: 44kDa

Gen-ID: 6999

NCBI Accession: NP_005642

UniProt: P48775