RPS19 Antikörper (C-Term)

Produktnummer ABIN5514788

Der Kaninchen Polyklonal anti-RPS19 Antikörper (ABIN5514788) detektiert spezifisch RPS19 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RPS19 Antikörper (C-Term) (ABIN5514788)

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RPS19 Antikörper

Bindungsspezifität: C-Term

Sequenz: SKSVARRVLQ ALEGLKMVEK DQDGGRKLTP QGQRDLDRIA GQVAAANKKH

Produktmerkmale: This is a rabbit polyclonal antibody against RS19. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RS19

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPS19

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Andere Bezeichnung: RS19

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Alias Symbols: RPS19,

Protein Interaction Partner: TP53, HUWE1, CEP250, NEDD1, TUBGCP4, TUBGCP2, PPP2R1A, AURKA, UBC, MDM2, RPS17, RNF2, WIBG, EIF2A, TSR1, SERBP1, EIF3E, FAU, RPS29, RPS28, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, RPS15, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6,

Protein Size: 145

Gen-ID: 6223

NCBI Accession: NP_001013

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly