GPS2 Antikörper (C-Term)

Produktnummer ABIN5514785

Dieses Anti-GPS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GPS2 in WB. Geeignet für Human.

Kurzübersicht für GPS2 Antikörper (C-Term) (ABIN5514785)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPS2 Antikörper

Bindungsspezifität: C-Term

Sequenz: TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT

Produktmerkmale: This is a rabbit polyclonal antibody against GPS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Andere Bezeichnung: GPS2

Hintergrund: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Alias Symbols: GPS2,

Protein Interaction Partner: ATF4, TFIP11, RBPMS, RALBP1, KRT31, SESTD1, NCOR2, HDAC3, SUMO1, UBC, TBL1X, TBL1XR1, vif, MSH5, MSH4, Nr0b2, NR1H4, HNF4A, HDAC1, NR5A2, HDAC5, THRB, THRA, CNOT2, SIN3A, PBK, C19orf57, GPS2, MAP3K7CL, CHD3, SPDL1, SETDB1, CCNA1, EP300, GOLGA2, NCOR1, TP5

Protein Size: 327

Gen-ID: 2874

NCBI Accession: XP_005256674

UniProt: Q13227