FGF12 Antikörper (N-Term)

Produktnummer ABIN5514765

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FGF12 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FGF12 Antikörper (N-Term) (ABIN5514765)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGF12 Antikörper

Bindungsspezifität: N-Term

Sequenz: QKRQARESNS DRVSASKRRS SPSKDGRSLC ERHVLGVFSK VRFCSGRKRP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FGF12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Andere Bezeichnung: FGF12

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alias Symbols: FHF1, FGF12B,

Protein Size: 167

Gen-ID: 2257

NCBI Accession: NM_004113, NP_004104

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity