LZTS1 Antikörper (N-Term)
Kurzübersicht für LZTS1 Antikörper (N-Term) (ABIN5514757)
Target
Alle LZTS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Verwendungszweck
- LZTS1 Antibody - N-terminal region
-
Sequenz
- LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG KSEDFFYIKV SQKARGSHHP
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 79%, Rat: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against LZTS1. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human LZTS1
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72909-100UG
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
-
Andere Bezeichnung
- LZTS1
-
Hintergrund
-
Background Information: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Alternative Symbols: F37, FEZ1
-
Molekulargewicht
- 65kDa
-
Gen-ID
- 11178
-
NCBI Accession
- XP_005273451
-
UniProt
- Q9Y250
-
Pathways
- Synaptic Membrane
Target
-