SIRT3 Antikörper (N-Term)

Produktnummer ABIN5514670

Der Kaninchen Polyklonal anti-SIRT3 Antikörper wird verwendet zum Nachweis von SIRT3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für SIRT3 Antikörper (N-Term) (ABIN5514670)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIRT3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SIRT3 Antibody - N-terminal region

Sequenz: AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA

Produktmerkmale: This is a rabbit polyclonal antibody against SIR3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SIR3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74220-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Andere Bezeichnung: SIRT3

Hintergrund:

Background Information: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Gene Name: sirtuin 3

Alternative Symbols: SIR2L3

Protein Name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Molekulargewicht: 43kDa

Gen-ID: 23410

NCBI Accession: NP_036371

UniProt: Q9NTG7