Opiorphin Prepropeptide (OPRPN) (N-Term) Antikörper

Produktnummer ABIN5514594

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Opiorphin Prepropeptide in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Opiorphin Prepropeptide (OPRPN) (N-Term) Antikörper (ABIN5514594)

Target: Opiorphin Prepropeptide (OPRPN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Verwendungszweck: OPRPN Antibody - N-terminal region

Sequenz: SFNYTTPDYG HYDDKDTLDL NTPVDKTSNT LRVPDILALV IFAVVFLVGV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C5AR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77605-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Opiorphin Prepropeptide (OPRPN)

Andere Bezeichnung: OPRPN

Hintergrund:

Background Information: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.

Gene Name: opiorphin prepropeptide

Alternative Symbols: BPLP, PRL1, PROL1, opiorphin

Protein Name: opiorphin prepropeptide

Molekulargewicht: 38 kDa

Gen-ID: 58503

NCBI Accession: NP_001727

UniProt: P21730