MRPL50 Antikörper (N-Term)

Produktnummer ABIN5514549

Produktdetails anti-MRPL50 Antikörper

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CREFWSRFRK EKEPVVVETV EEKKEPILVC PPLRSRAYTP PEDLQSRLES

Homologie: Cow: 85%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RM50. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RM50

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPL50

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Andere Bezeichnung: RM50 (MRPL50 Produkte)

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Alias Symbols: MRPL50,

Protein Interaction Partner: UBC, MDM2, NPM1, MRPL45, TMEM177, MRPL57, MRPL44, MRPL32, MRPL38, MRPL40, MRPS9, MRPL47, TSR1, RIF1, MRPL37, MRPL15, FLOT1, MRPL19, SUCLG2, SLC25A3, ILF2, ATP6V0A1, ATP6V1B1, CUL3, ICT1,

Protein Size: 158

Gen-ID: 54534

NCBI Accession: NP_061924

UniProt: Q8N5N7