Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) Antikörper
Kurzübersicht für Neural Wiskott-Aldrich syndrome protein (WASL) (N-Term) Antikörper (ABIN5514539)
Target
Alle Neural Wiskott-Aldrich syndrome protein (WASL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- FANEEEAKKF RKAVTDLLGR RQRKSEKRRD PPNGPNLPMA TVDIKNPEIT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human WASL
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Neural Wiskott-Aldrich syndrome protein (WASL)
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Andere Bezeichnung
- WASL
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Hintergrund
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This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
Alias Symbols: NWASP, WASPB, N-WASP
Protein Interaction Partner: RHOJ, ARPC3, RNF8, NCK2, WIPF1, SDCBP, PTK6, GRB2, IQGAP1, WWOX, SNX9, APBB1, PRPF40A, FNBP1L, FNBP1, TRIP10, PSTPIP1, ACTG1, SORBS3, ACTR2, ACTR3, LCK, CDC42, RPL7AP66, ZNF395, BAIAP2, ARPC1B, FCHSD2, IPO5, HP, HSP90AB1, HSP90AA1, SRC, WASF2, APP, WIPF2,
Protein Size: 505 -
Gen-ID
- 8976
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NCBI Accession
- NM_003941, NP_003932
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UniProt
- O00401
Target
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