Arhgef9 Antikörper (C-Term)

Produktnummer ABIN5514508

Der Kaninchen Polyklonal anti-Arhgef9 Antikörper wird verwendet zum Nachweis von Arhgef9 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Arhgef9 Antikörper (C-Term) (ABIN5514508)

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Arhgef9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Arhgef9 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ARHGEF9 Antibody - C-terminal region

Sequenz: VPKQKGVNSA RSVPPSYPPP QDPLNHGQYL VPDGIAQSQV FEFTEPKRSQ

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF9

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77160-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Arhgef9

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Andere Bezeichnung: ARHGEF9

Hintergrund:

Background Information: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: Cdc42 guanine nucleotide exchange factor (GEF) 9

Alternative Symbols: DEE8, PEM2, EIEE8, PEM-2, HPEM-2, COLLYBISTIN

Protein Name: rho guanine nucleotide exchange factor 9

Molekulargewicht: 61 kDa

Gen-ID: 23229

NCBI Accession: NP_001166950

UniProt: O43307

Pathways: Neurotrophin Signalübertragung